Sentence examples for define specificity from inspiring English sources
In this case, an Asn in the transmembrane domain provided a strong driving force for folding but failed to specify a unique oligomerization state, while an Asn in the water-soluble domain was able to define specificity for a specific aggregation state as well as modulate stability.
In order to feed the software, we generated an alignment of alignments, comprising six yeast PATs and their orthologue groups (as defined in ORTHOMCL) making the assumption that they define specificity groups (see below).
In order to define specificity and crosstalk among the transcriptomic responses for the studied treatments, we analysed overlapping of downregulated and upregulated genes for S, SA and MA treatments.
20 A study that interviewed GPs to elicit their definitions of various accuracy parameters found that only 1/13 could define PPV, 1/13 could define some aspects of sensitivity and 0/13 could define specificity.
Hence, two UIMs are present in Rap80, not only to increase affinity, but also to define specificity through the intervening amino acids; these form a molecular ruler that directs the two ubiquitin-binding surfaces in roughly the same direction and separates their centres by 37.5 Å, two attributes optimal for binding to K63-linked chains.
As depicted in Fig. 5B, PDZ6, which binds β-catenin (Dobrosotskaya and James, 2000), is well conserved in all metazoa analyzed, including the residues that define specificity (Tonikian et al., 2008), suggesting that the MAGI1-β-catenin link is conserved as far back as sponges.
The authors also define specificities of hydrophobic binding residues qualitatively using pull-down assays.
> -wrap-foot> The ability to predict false negatives in glycan array data is essential in order to fully define specificities and binding motifs.
CsrA has a clearly defined specificity based on binding to a specific mRNA sequence to inhibit translation.
The variants have a defined specificity, as they could be shown to specifically target galactose-decorated xyloglucan structures (such as XLLG).
The multi-epitope contraceptive vaccines and preformed engineered antibodies of defined specificity may eliminate concern related to inter-individual variability of the immune response.
