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The modules define sites of interaction with the outer membrane transport genes, TonB, the immunity proteins, and the activity regions.
Successful strategies include making educated guesses based on protein primary sequence, using binding studies to define sites of protein-protein interaction, and designing peptides based on the three-dimensional structure of known sites of interaction.
To further evaluate the contribution of infected-cell proliferation to HIV persistence, we developed a method (integration site loop amplification (ISLA)) to define sites of HIV integration in single cells and sequence up to 2.8 kb of the 3′ region of the viral genome adjacent to the integration site, allowing us to link specific viral variants to specific integration sites (fig. S1).
They may define sites of protein interaction with DNA or other proteins, based on ontology analysis.
It is essential to define sites of TGF-β1 and HGF/SF signaling.
Glass substrates were micropatterned with PEG hydrogels to define sites for binding of aptamer beacons.
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Knowledge of wind characteristics helps to define site requirements, choose a proper turbine design and estimate profits from the wind energy production.
Other mAbs define site-specific T antigens, such as BW835 with the VTSA motif in MUC1 tandem repeat.
For comparative purposes, we also apply current methods used in the literature and show how these may fail to define site-specific losses.
Using this approach, the site composition of five defined sites with increasing size up to 8 nm was obtained.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com