Sentence examples for define responses from inspiring English sources

A range of technical platforms are used preclinically to define responses to therapy, the most informative of which are adopted for use in patients.

Modern genome-wide approaches may offer a possible solution and are increasingly being used to unravel the molecular mechanisms that define responses to environmental stressors and to predict their adverse effects on critical biological pathways.

However, conventional CR can be associated with a significant residual disease burden and MRD assessment as evaluated by sensitive flow cytometric and molecular techniques can further define responses in patients in CR to those as MRD-negative CR with significantly improved PFS and OS compared with those who achieve CR but are MRD positive.

We densely characterized early ctDNA dynamics during therapy using cancer personalized profiling by deep sequencing to define response-associated thresholds within a discovery set.

We envision that ULP-WGS can be used in sequential samples during therapy to define response and progression but more importantly, those samples can be further analyzed for the specific resistant clones that emerge during therapeutic interventions in these patients.

We define response in terms of two conditions: reservoirs either below (under) or above (over) the saturation pressure that defines the permeability minima in the reservoir.

Montgomery-Asberg depression rating scale (MADRS) scores and clinical global impression (CGI) severity scores were used to define response.

Additional effort is required to define response to OBT-A and to establish optimal treatment duration.

Cut-offs of ≥25%, ≥50%, ≥75%, and 100% reductions from baseline in attack frequency were used to define response.

In this approach NNT is dependent on the threshold to define response on the continuous scale.

WHO criteria were used to define response.