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To represent the specificity of SH2 domains in this study we define position weighted matrices (PWMs) based on the array-positive peptides.
If it were impossible to exactly define position, then "holographic noise" should cause the output of an interferometer to jiggle at a frequency of millions of cycles per second, he argued.
Tandem gene arrays are among the most challenging parts of genome sequences to assemble, for much the same reason that non-coding repetitive regions are difficult to resolve; assembling sequence reads into contigs relies on unique motifs to define position.
In this study, we define position control genes (PCGs) as genes that (1) display regionalized expression along one or more body axes, and (2) either show a patterning-abnormal RNAi phenotype (e.g., homeotic) or encode a protein that is predicted to regulate pathways (e.g., Wnt, Bmp, or Fgf signaling) that are important for planarian patterning (Reddien, 2011).
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Very likely, other features, such as gene density, rather than the newly acquired or lost functions, define positioning in the nucleus.
First, some background: an institution may be identified by a system of rules that define positions, moves, penalties, rewards, etc.
This helped to define positions for substitution, which could lead to a greater thermostability without losing or diminishing enzyme activity.
We use these grids to either define static absolute locations across a cortical sheet or to define positions relative to the location of a neuron soma.
Individuals are more likely to accept a job if the overall WTP for a defined position is positive.
It's a nebulously defined position, yet a critical one.
Odinga had to settle for the less powerful and poorly defined position of prime minister.
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