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We chose to use GO and KEGG to define pathways since they are publicly available in a format that enables systematic testing of all pathways simultaneously in a statistically rigorous manner.
We used pharmacometabolomics to define pathways implicated in variation of response to treatment.
These results define pathways by which cells resist TLD and suggest strategies for combating TLD resistance during chemotherapies.
The Diana miRpath application [ 32] was used to define pathways enriched in the predicted targets for CC significant miRNAs.
Further studies on mechanisms underlying reduced kidney pericyte number in aging are needed to define pathways that lead to fibrosis.
In this study we define pathways by which UvrD, RuvABC, and RecBCD allow cells to resist TLD.
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In summary, we provide a tool for the measurement of synergy strength for combination perturbation experiments that might help define pathway topologies and direct clinical trials.
As β-catenin staining had not been carried out on this cohort we used AXIN2 expression to define pathway activation.
It employs the widely used SAM software package to define "pathway signatures" from known molecular perturbations [ 4].
Most proteins fold into their native structure through defined pathways which involve a limited number of transient intermediates.
The results are important for predictions based on experimentally measured energy distribution functions, and for defining pathways for the preparation of individual crystalline phases in general.
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CEO of Professional Science Editing for Scientists @ prosciediting.com