Pressure transient data collected during the hydraulic tests were analyzed using the well-test simulator nSIGHTS to estimate the hydraulic properties specified as fitting parameters for the tested intervals, quantify parameter uncertainty, and define parameter correlations.
Finally, in order to take into account practical implementation issues, we define parameter dretx as the delay (in number of time slots) between reception of feedback and the next repetition in NDMA and H-NDMA protocols (see explanation in Section 2.1).
Step 1 generate the facies model, define parameter a and generate Y 0, an initial Gaussian white noise (see Eq. 4), Step 2 generate U, a complementary Gaussian white noise, Step 3 enter the gradual deformation loop that drives the t deformation parameter, a. Combine Y o and U to obtain Y. b.
These results define parameter boundaries for the use of ESCs in screening studies, demonstrate the importance of context in stem cell responsiveness to exogenous cues, and suggest that niche size is an important parameter in stem cell fate control.
As additional data become available, our model could be re-calibrated to better define parameter posterior distributions.
At present, two baseline scans are recommended for all studies (to define parameter reproducibility) (Leach et al, 2005), but guidelines on the timing of MRI scanning and the choice of imaging parameters are less clear.
