Sentence examples for define mechanism from inspiring English sources
Here were identify three additional compounds recovered in this screen and provide a detailed account of the screening assay and the results of newly devised secondary assays designed to define mechanism of action and prioritize compounds for testing in mammalian models.
Future studies should focus on the effect of alterations to the GSDMB isoform pool on factors such as the inflammatory milieu in other appropriate cell types to prove causality and further define mechanism.
We will also identify the possible presence of pertinent sequence elements flanking TGAs (such as transposon sequences, replication origins and small conserved DNA motifs) in order to define mechanism(s) of TGA formation.
No short-term killing assays, e.g., Annexin-PI or molecular approaches were included to further define mechanism(s) of interaction, however it was of note that a simple correlation between the PARP inhibitor-induced reduction in PAR levels and drug effects did not simplistically correlate.
This is clearly a complex question, and further research is necessary to define mechanisms of toxicity of AuNPs.
Our findings define mechanisms of APC/C regulation, and establish principles by which specialized E3 E2 substrate-UB architE3 E2 substrate-UBfferent forms of polyubiquitinarchitectures
Mapping of neutralising epitopes using monoclonal antibodies (mAbs) helps define mechanisms of antigenic drift, neutralising escape and facilitates pre-pandemic vaccine design.
Hence, it is crucial to correctly categorize HER2 amplified tumors and define mechanisms of resistance to design effective new treatment approaches.
Our goal was to define mechanisms that protect murine pregnancies deficient in spiral arterial remodeling from hypertension, hypoxia, and intrauterine growth restriction.
Outside the plant organosulfurs, there are no comprehensive reviews of these areas to help define mechanisms by which organosulfurs function as well as identify potential alternative uses.
Epitope mapping using neutralizing monoclonal antibodies (mAb) helps define mechanisms of antigenic drift, neutralizing escape and can facilitate pre-pandemic vaccine design.
