Exact(1)
The environmental deposition of chemical pollutants requires surveillance strategies to detect and warn of potentially detrimental and hazardous exposure events and to define endpoint remediation metrics when contaminated sites are destined for cleanup.
Similar(59)
Although the focus of this report is on the development of a new COA to define endpoints in a clinical trial, these principles may be applied more generally.
With the increasing number of novel agents and delivery techniques being explored in clinical trials there is a strong need for robust and adaptable criteria to monitor response assessment and thus define endpoints.
The web appendix defines the ICD-10 codes used to define endpoints and comorbidities (table w1).
The lack of consistent assessment of PONV is an issue because studies often define endpoints differently.
The trial that assessed efficacy and safety of adding abatacept to mycophenolate mofetil (MMF) highlights the need to define endpoints carefully [ 26].
Far more difficult is the question of what to do with the 32 so-called "forever prisoners" whom the review recommended for continued detention without trial until the end of a "war on terrorism" that has no defined endpoint.
Despite this, most interview respondents said their biobank had no defined endpoint.
The skin sensitisation is a well defined endpoint of specific utility within the REACH framework.
A (Q SAR model for regulatory purposes should be associated with the following information: 1) a defined endpoint 2) an unambiguous algorithm 3) a defined domain of applicability 4) appropriate measures of goodness-of-fit, robustness and predictivity 5) a mechanistic interpretation, if possible. . a defined endpoint.
(i) The actual defined endpoint is defined as the excessive apoptosis with the TD50 rate (in mg/kg body wt/day) of carcinogenic potency in rats derived from the Carcinogenic Potency Database [28].
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