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Here, we define a requirement for the INO80 complex, a SWI/SNF family chromatin remodeler, in ESC self-renewal, somatic cell reprogramming, and blastocyst development.
Using additional synthetic ligands and their binding proteins that recruit ZAP70 equally well but orient it at the cell membrane in different ways, we define a requirement for a specific presentation of ZAP70 to its downstream targets.
In particular, the work described uses control theory to define a requirement engineering (RE) process control system, its dynamic and steady-state performance, and the steps in designing, analyzing and improving such a system.
The results indicate differing roles for Rpn13 and Uch37 in mammalian development and furthermore define a requirement for Rpn13 in gametogenesis.
Importantly, we define a requirement for pdx1 in latent, duct-associated, Notch-responsive progenitors responsible for the production of second wave endocrine cells.
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Kabanda et al. [15] define a requirements meta-model for software systems that incorporates social features: users, policies, and culture.
This effect defines a requirement for particular size and shape of the protruding residues, and it is associated with a relative axial translation of the paired helices.
For this specific combination (adult and pediatric autologous HSCT) JACIE has not defined a requirement.
Together, this data defines a requirement to keep the carrier DNA within a given window for quantitative analysis.
Using a functional genomic approach, we have defined a requirement of pre-mRNA splicing factors for sister chromatid cohesion in human cells.
Our findings modify previously described mechanisms in Src-induced tumour angiogenesis [ 13] by defining a requirement for ezrin and its phosphorylation by Src in this process.
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CEO of Professional Science Editing for Scientists @ prosciediting.com