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Previously, we used live-cell imaging of six budding-yeast proteins to define a pathway for association of receptors, adaptors, and actin during endocytic internalization.
This is in agreement with the fact that the morphologies obtained during the evolution correspond to out-of-equilibrium configurations and define a pathway towards the global energy minimum.
In this paper we define a pathway analysis, based on static analysis techniques from programming languages, and show how it can be used to establish useful, finite, approximations to the set of causal consequences of models.
However, Tomfohr, et. al. do not use the network structure knowledge to obtain scores, but instead perform Singular Value Decomposition (SVD) to choose a specific metagene, and define a pathway activity as the expression of that gene.
SAFE [ 47] enables the user to define a pathway enrichment statistic and a Pearson test of binomial proportions was then implemented [ 48].
Persad et al. (2001b) define a pathway that ILK and GSK-3 can regulate β-catenin stability, nuclear β-catenin expression, and its transcriptional activity.
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We define a pathway-summary function S, which aggregates all pathway vectors for a given task.
Objective: The purpose of this paper is to describe the philosophy and utility of value-based designs (VBDs), with an eye toward defining a pathway for a shift to VBDs across US businesses involved in the health care discussion.
Despite the functional framework that defines a pathway for SBDS protein family as described above, its biochemical property that contributes to its involvement in the cytoplasmic recycling of Tif6p and ribosomal P-site maturation remains unclear.
We propose that ObgE defines a pathway analogous to the replication checkpoint response of eukaryotes and acts in a complementary way to the RecA-dependent SOS response to promote bacterial cell survival to replication fork arrest.
The proposed single cell investigation constitutes the first step toward defining a pathway to map metal reduction sites to better understand the mechanisms involved in the reduction of Cr VI) to Cr III).
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