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As an extension, both ChEBI and the GO will define a nucleotide as 'a phosphate ester that has a nucleoside moiety AND has at least one phosphate moiety attached to the C-5 carbon of the ribose or deoxyribose moiety'.
For a word W, we define a nucleotide substitution matrix [ W pi ], which contains words that are derived from W by placing a nucleotide i in a position p (Fig. 1A).
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All 12 sequences in this region have high similarity to the derived consensus sequence GXGXXG 7X A SX GXGXXG(4X)D(9X)R, which defines a nucleotide binding motif [ 16, 25].
We provide functional data to show that SNPs can lead to the expression of antisense RNA, a finding with implications for how we define a 'silent' nucleotide change.
For a small number of reads that matched UniProt entries but no conserved genes or UniGenes, it was not possible to define a reference nucleotide sequence.
We provide genomic, transcriptomic and functional data to show that synonymous point mutations (sSNPs) on the coding strand can lead to the expression of antisense transcripts on the opposing strand, a finding with implications for how we define a 'silent' nucleotide change.
Herein we describe a series of experiments that define a single polymorphic nucleotide within the H. pylori sodB promoter that is important for apo-Fur dependent regulation.
For example, it is easy to define a format for nucleotide data where gaps are coded as a fifth state or for binary data.
In each case, we define a 7-mer nucleotide sequences based on the small RNA read with the highest copy number throughout the control, low and high risk MDS samples.
Using the extensive collection of Tetrahymena species in the American Type Culture Collection these authors defined a 689 nucleotide cox1 barcode and provided ~1600 2300 SSU nucleotide sequences for most named Tetrahymena species.
Our CGI annotation was based on the criteria by Takai and Jones (Takai & Jones, 2002), which define a CpG island as a nucleotide sequence of 200 bp or greater in length or with a GC content of 50% or more, or a ratio of observed versus expected CpGs of 0.6 or higher.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com