Sentence examples for define a checkpoint from inspiring English sources
Sustained downregulation of TCRzeta may define a checkpoint where the intracellular signals driving T-cell differentiation switch from antigen mode to inflammation mode.
We propose that sustained downregulation of the TCRζ chain defines a checkpoint where intracellular signals driving T-cell differentiation and effector responses switch from antigen mode to inflammation mode, where effector function may be largely antigen independent.
These data have contributed to defining a regulatory checkpoint of erythropoiesis and support the rationale to develop sotatercept for the treatment of anaemia and ineffective erythropoiesis.
Thus, we have verified that the restrictions define an optimal first checkpoint.
A mechanism to coordinate the timing of two potentially independent events during the cell cycle is defined as a checkpoint.
Whether this 60-hour checkpoint also defines a window in which FUS3 can reactivate late embryogenesis programming needs to be determined, but our expression studies place postembryonic FUS3 within this developmental window.
We propose that ObgE defines a pathway analogous to the replication checkpoint response of eukaryotes and acts in a complementary way to the RecA-dependent SOS response to promote bacterial cell survival to replication fork arrest.
After Pro-MI, we defined a short stage shortly before MI as latePro-MI to study details of Bub3 localization because the Pro-MI-MI transition is a crucial time point for tracing the behavior of checkpoint proteins.
For me, I need more perspective, more life experience in order to define my checkpoints.
