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Transgenic R6 lines of HD mice have been well characterized and model many HD symptoms and neuropathology, including progressive cognitive decline, motor deficits, weight loss and neuronal dysfunction [5] [10].
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Results: The mean endometrial thickness, fluid used, fluid deficit, weight of resected tissue and duration of surgery were significantly greater in the unprepared group.
Apart from the 2 randomized controlled trials on sibutramine included in the current meta-analysis, James et al (41) also found a large effect of sibutramine on weight-loss maintenance after a 600-kcal/d deficit weight-loss program.
The total number of infants with deficits involving weight-for-age, weight-for-height, and height-for-age were 15.1%, 11.3%, and 23.9%, respectively.
Neurological deficits, body weight, infarct volume, and histology were analyzed.
Here, nutritional insufficiency leading to deficits in weight and/or growth (particularly during the key developmental periods of gestation and lactation) when coupled with postnatal nutritional excess increase the risk of adult metabolic disease [43] [45] and actually reduce lifespan in male mice [7].
Deficits in weight gain and BMI increases were more apparent than deficits in growth.
As hyperbilirubinemia proceeded, mutant mice showed severe neurological deficits and weight decrease.
Rage deletion had no significant impact on glycaemia (based on HbA1c) or characteristic deficits in weight gain.
There is evidence that older adults who eat alone have increased risks of nutritional deficits, poor weight control [ 7– 9] and death [ 10, 11].
However, little is known about the effects of nutritional deficits on weight gain, or how to meet nutrient requirements for restoration of nutritional status.
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