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The frailty index score expresses the number of deficits present as a proportion of the total number of deficits [ 25].
These deficits present as increased step width, variable foot placement, irregular foot trajectories, and a resulting instable stumbling walking path with very high movement variability [ 6– 8] and a high risk of falling [ 9].
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Less ATP availability ultimately results in an energy deficit presenting as reduced cardiac efficiency and contractile dysfunction.
Patients with tumor corresponding neurological symptomatology (epileptic seizures, focal neurological deficit) present at least 6 months before the tumor diagnosis was considered as likely secondary GBM.
We documented previously on time reproduction deficits present in both children with ADHD as well as their non-affected siblings (Rommelse et al. 2007b), suggesting familial deficits in timing in ADHD generalize across timing paradigms and extent beyond motor timing as reported in the current study.
Frailty indices count the number of deficits present and describe these as a proportion of all deficits assessed; individuals with an FI of >0.25 are at an increased risk of adverse outcomes [ 18].
The Frailty Index represents the burden of health deficits, expressed for an individual as the proportion of deficits present – from 0 (no deficits) to 1.0 (the theoretical maximum, if all deficits were expressed).
The index is often expressed as a ratio of deficits present to the total number of deficits considered.
The FI score was defined as the proportion of deficits present.
An FI is constructed as the proportion of deficits present in an individual out of the total number of age-related health variables considered.
In brief, the FI evaluates the extent to which deficits are accumulated in a given person, which is quantified as the proportion of the deficits present in this person (that is the number of deficits present divided by the total number of potential deficits that were considered).
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