After prolonged exposure to TiO2-NPs, nematodes exhibited severe deficits in development of intestinal barrier and AVL and DVB neurons controlling defecation; however, after acute exposure to TiO2-NPs, nematodes had normal developmental state of intestinal barrier and AVL and DVB neurons.
Deficits in development of central cholinergic pathways caused by fetal nicotine exposure: differential effects on choline acetyltransferase activity and [3H]hemicholinium-3 binding.
Perturbations in BMP, FGF, Wnt (both canonical and non-canonical), and Nodal signaling prior to and during gastrulation lead to later deficits in development of Nkx2.5-expressing myocardial progenitors (Reifers et al., 2000; Reiter et al., 2001; Ueno et al., 2007).
To further investigate whether gustatory deficits are involved in development of the feeding alterations, IL-1β induced changes of taste responsiveness were also studied in taste reactivity tests.
Finally, functional analysis of RGCs targeting the tectum reveals a selective deficit in the development of orientation selectivity after Teneurin-3 knockdown.
Dyslexia involves an unexpected deficit in the development of reading skills whereas SLI refers to an impairment in the acquisition of oral language (Pennington and Bishop 2009).
Therefore we conclude that inhibited neurogenesis can play an active role in development of cognitive deficits and progression of the AD.
Besides functional deficits, almost all types of nerve lesions could result in development of neuropathic pain.
As previous studies have implicated chloride current deficits in the development of myotonia in the HSA LR mouse model and mice lacking Mbnl1 (Kanadia et al., 2003; Mankodi et al., 2002), we examined the function of these channels in mice lacking either Mbnl1 or Mbnl3 and in animals deficient in both Mbnl1 and Mbnl3.
These health-based standards were based on avoiding MeHg-associated delays and deficits in neurologic development of children after in utero exposure to MeHg (Mergler et al. 2007; Rice et al. 2003).
