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AD participated in the design of the study, derived one of the base deficit formulae and advised on data analysis.
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The dose of iron needed may be assessed using the following formula: iron deficit = body weight (kg ) × (target Hb − actual Hb ) × 2.4.
Equation [9] is Shannon's formula for H = uncertainty, which we have called data deficit (actually, Shannon's original formula includes a positive constant K which amounts to a choice of a unit of measure, bits in our case; apparently, Shannon used the letter H because of R.V.L. Hartley's previous work).
Dosing methods vary widely with study design and physician preference, and these are summarized in Table 2. Concentrated bicarbonate dosing based on calculations using predictive formulas incorporating base deficit [37, 38] results in a tendency for over-correction and alkalosis [29, 30].
Our secondary hypothesis was that the loss of accuracy as a consequence of applying these abbreviated formulae to the base deficit would not be great enough to compromise clinical validity.
Yet finding that compromise looks harder than ever.Mr Obama proposed much the same formula to reduce the deficit and avert the sequester as he has previously, though never in so elevated a forum.
For this reason, the paper has proposed one design formula to make up the deficit based on yield line theory.
In hindsight, many economists say, the United States should have recognized that borrowing from abroad for consumption and deficit spending at home was not a formula for economic success.
It was the absence of the flexibility to do so, in the last decade, that contributed to a massive structural deficit and, later, sharp tax increases as formulas dictated ambitious spending targets, especially on public schools.
Over time, the SGR formula has created a huge deficit in Medicare's budget, which has been patched on an ad hoc basis by Congress.
The many closed-door meetings in Washington to decide on America's future are filled, instead, with esoteric and magical formulas purporting to close the deficit.
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