Sentence examples similar to deficient repairs from inspiring English sources

The disease xeroderma pigmentosum is characterized by deficient repair of damaged DNA.

Deregulation of this hierarchy has been described in several tumors4,5,6, leading to deficient repair and genetic aberrations.

We conclude that in a general manner "bad bugs" have a deficient repair system that renders them incapable of repairing any mutation and of overcoming gene degradation that will eventually lead to pseudogenization and total gene loss.

This suggests that cell death contributes to matrix degradation and deficient repair.

Mitochondrial DNA is especially prone to oxidative damage due to its proximity to a primary source of ROS and its deficient repair capacity compared with nuclear DNA.

Under normal conditions, the levels of DNA damage and the capacity of DNA repair systems maintain a dynamic balance; and deficient repair systems can result in either altered apoptosis or unregulated cell growth that leads to carcinogenesis[ 7].

However, there is also experimental evidence that ionising radiation induces various molecular changes in breast epithelial cells and that a BRCA1-mutated breast cancer cell line shows deficient repair and increased chromosomal aberration (Mamon et al, 2003).

In addition to highlighting the ineffectiveness of current exacerbation treatments [ 38, 39], these findings suggest that a deficient repair response similar to that observed in vitro[ 21, 40, 41] is present within the airway epithelium of asthmatics during exacerbation.

Reduced expression of DNA repair genes causes deficient DNA repair.

After an inspection in 2005 engineers had classified the bridge as "structurally deficient", and repairs were planned.

The failure of, or the presence of deficient DNA repair capacity for each specific DNA-repair pathway may contribute to an increase in cancer risk.