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The gene most strongly regulated by miR-29 is IL12B (encoding IL-12/23 p40) while IL23A (encoding IL-23 p19) is indirectly targeted through suppression of its transcription factor ATF2 and mice deficient of this miRNA develop a more severe Th17 driven colitis on DSS exposure.
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Australia's play seemed lacklustre and deficient of the ruthlessness we are accustomed too.
Mice deficient of the core NMD component UPF2 die in utero around E3.5-E7.5 E3.5-E7.5 [13]
The complications resulting from deficient control of this condition can lead to poor quality of life for the patient and considerable health care costs.
The 81116AI2- variant is the AI-2 deficient clone of this strain maintained and passaged in the author's laboratory.
Together with the absence of activity in the right parahippocampus during the encoding phase, deficient functioning of this network may underlie distortions in memory for time in PD [9], and may be an early marker of memory problems.
In the apparent absence of changes in the p50 content, the downregulation of p50 homodimer DNA-binding in chronic alcoholics may occur due to the deficient phosphorylation of this protein (Figure 6).
Proficient or deficient function of this downstream apoptosis signaling checkpoint is subsumed by the parameter 'cc-related activation of caspase-3 (CRAC)'.
In contrast to sheep [ 46] and cattle [ 45] very few pathological lesions were seen in the Cu and Cr deficient goats of this study although they had been subjected to a rather severe trace element deficiency and/or imbalance.
(soluble mannose-binding lectin 2, synonym: protein C) contains the SNP marker (rs72661131) of variable immunodeficiency [ 110], preeclampsia [ 111], and stroke [ 112] caused by deficient expression of this gene as we have also predicted in silico [ 83] and confirmed under both equilibrium [ 79] and nonequilibrium [ 80] conditions in vitro.
In the case of deficient secretion of this hormone as occurs in the medical condition of diabetes insipidus there is marked elevation of water loss in the urine.
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