"deficient integration" is a correct and usable phrase in written English.
It is typically used to describe a lack of effective merging or combining of various elements or components. It can be used in various contexts, such as in discussing problems with systems or processes, relationships between individuals or groups, or understanding of concepts. Example: The new software program's deficient integration with other applications has caused numerous technical issues for the company.
Finally, we identify functional contracting as a solution for value-based sellers to overcome the barriers arising from deficient precontractual integration.
Thus, impaired time perception in PD may be partially related to deficient striatal integration of cortical input.
Lentiviral vectors deficient for integration offer great potential for therapeutic vaccination but the demonstration that they can elicit effective protective immunity opens also for the first time the possibility of using lentiviral vectors in large-scale prophylactic vaccinations.
Interestingly, it has been recently described that HAB mice also present with reduced hippocampal neurogenesis (9), generally accepted as one of the cellular correlates of depression-like behavior and deficient functional integration of the newly born cells (for review see (13)).
Schizophrenics might be deficient in perceptual integration during processing in the extrastriate cortex, which might consequently increase the loads needed for higher processing in the prefrontal cortex reflected by the enhanced fMRI activation in ACC.
For transient expression of Y2-I-AniI, a lentiviral vector with a short form of EF1α driving Y2 I-AniI.2A.mCherry was constructed and used to produce integration deficient lentiviral vector (IDLV).
In this respect, the development of integration deficient lentiviral vectors circumvents the safety concerns relative to insertional mutagenesis and might pave the way for clinical applications in which gene transfer is targeted to non-dividing cells.
To test the hypothesis that integration deficient lentiviral vectors could be efficient tools to deliver Ags to non-dividing antigen-presenting cells such as DC, we initially evaluated their transduction efficiency in growth-arrested cells.
However, in a NHEJ-deficient background, ectopic integration is not favoured and the complementing gene construct will preferably integrate at its endogenous (deleted) locus.
