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Exact(2)
Thirteen interfaces with misorientation angles varying between θ = 3° and θ = 22.6° were studied in both stoichiometric and oxygen deficient forms.
Although both Tal1/Scl and E47 associate with Skp2 independently and are apparently ubiquitinated by SCFSkp2, overexpression of chaperone-noninteracting and E3 ligase deficient forms of CHIP or knockdown of endogenous CHIP diminishes Tal1/Scl and E47 ubiquitination.
Similar(58)
In the Mohists' defense, one might argue that all goods at least produce some general feeling of satisfaction, if not delight, and that things that do not genuinely benefit us produce at best only a transient, unstable, or otherwise deficient form of satisfaction or delight.
We used TG2-C277S as a transamidation inactive form and TG2-R580A as a GTP-binding deficient form having greater transamidating activity.
Accordingly, the autoimmune hypothesis of narcolepsy might be true only for the HLA DR2 positive or the central orexin deficient form.
We used two mutants of DMPK: myc-K110ADMPK, a kinase deficient form mutated at the ATP-binding site [28], and myc-ΔMADMPK, which lacks C-terminal residues 550-629 but retains kinase activity [22].
However, few laboratories can successfully culture the cell wall deficient form of MAP that exists in humans [14], [30], [31], a process that may take up to 18 months.
Cells expressing a GTP binding deficient form of TG2 TG2-R580AA) withighgh basal transamidation activity and a more extended conformation showed significantly increased cell death in response to oxygen-glucose deprivation; however, targeting TG2-R580A thethe nucleus abrogated its detrimental role in oxygen-glucose deprivation.
Again, the specificity of BiFC was confirmed with a DNA-binding deficient form of Exd.
We tried to validate the specificity of these interactions by using a DNA-binding deficient form of AbdA.
(B ) Interactome with the DNA-binding deficient form of AbdA (mutated in the residue 51 of the HD, as illustrated with the red bar).
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Justyna Jupowicz-Kozak
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