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Givogri, M.I. et al. Central nervous system myelination in mice with deficient expression of Notch1 receptor.
Givogri, M. I. et al. Central nervous system myelination in mice with deficient expression of Notch1 receptor.
Deficient expression of PPARγ can be a significant risk factor for carcinogenesis, although in some cases overexpression enhances carcinogenesis.
Patients with the deficient expression of selectin ligand by neutrophils suffer from recurrent infections, persistent leukocytosis and severe growth and mental retardation.
Emphasis is put on the role of abnormal intratumorous T cell selection and activation, lack of intratumorous myoid cells and regulatory T cells as well as deficient expression of the autoimmune regulator (AIRE) by neoplastic thymic epithelial cells.
Deficient expression of fragile X mental retardation protein (FMRP) underlies the molecular mechanism of fragile X syndrome (FXS).
Deficient expression of DNA repair proteins due to an inherited mutation can cause increased risk of cancer.
Duchenne muscular dystrophy (DMD) is caused by deficient expression of the cytoskeletal protein, dystrophin.
The CNS normally is in an immunologically quiescent state, due to deficient expression of MHC molecules, and limited entry of infiltrating T-cells into the brain parenchyma.
We have tested Salmonella Typhimurium with AvrA sufficient or deficient expression in a cultured polarized human epithelial cell model, an animal model, and in AvrA-transfected cells.
[30] A recent in vivo study [31] demonstrated an impaired development of human Th1 cells in patients with deficient expression of STAT4.
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