Sentence examples for deficient expression of from inspiring English sources
Deficient expression of fragile X mental retardation protein (FMRP) underlies the molecular mechanism of fragile X syndrome (FXS).
Deficient expression of PPARγ can be a significant risk factor for carcinogenesis, although in some cases overexpression enhances carcinogenesis.
Patients with the deficient expression of selectin ligand by neutrophils suffer from recurrent infections, persistent leukocytosis and severe growth and mental retardation.
Emphasis is put on the role of abnormal intratumorous T cell selection and activation, lack of intratumorous myoid cells and regulatory T cells as well as deficient expression of the autoimmune regulator (AIRE) by neoplastic thymic epithelial cells.
Deficient expression of DNA repair proteins due to an inherited mutation can cause increased risk of cancer.
Duchenne muscular dystrophy (DMD) is caused by deficient expression of the cytoskeletal protein, dystrophin.
Furthermore, given the synergistic interaction with KRAS mutations, an early and ubiquitous genetic event in the development of PDA and the clinical significance of deficient expression, development of agents that increase STAG2 expression may provide a strategy for both treatment and prevention.
Hereditary hemochromatosis (HH) encompasses genetic disorders of iron overload characterized by deficient expression or function of the iron-regulatory hormone hepcidin.
Mice that expressed the SmoA1 transgene and that were either wild-type or deficient in expression of Pten were prone to development of tumor in the developing mouse cerebellum.
Thymocytes deficient in expression of the TGF-βRII also developed normally into Foxp3+ Treg (Li et al., 2006; Marie et al., 2006).
Using cells deficient in expression of glycosaminoglycans (GAGs) and short hairpin RNAs reducing heparan sulfate (HS) and chondroitin sulfate (CS) expression, we found that intracellular HS and CS (= GAGs) partly controlled the trafficking of CCL2 from the Golgi toward secretion.
