Sentence examples for deficient expression from inspiring English sources

Deficient expression of fragile X mental retardation protein (FMRP) underlies the molecular mechanism of fragile X syndrome (FXS).

Deficient expression of PPARγ can be a significant risk factor for carcinogenesis, although in some cases overexpression enhances carcinogenesis.

Patients with the deficient expression of selectin ligand by neutrophils suffer from recurrent infections, persistent leukocytosis and severe growth and mental retardation.

Emphasis is put on the role of abnormal intratumorous T cell selection and activation, lack of intratumorous myoid cells and regulatory T cells as well as deficient expression of the autoimmune regulator (AIRE) by neoplastic thymic epithelial cells.

Deficient expression of DNA repair proteins due to an inherited mutation can cause increased risk of cancer.

Duchenne muscular dystrophy (DMD) is caused by deficient expression of the cytoskeletal protein, dystrophin.

In fact, the CoQ10-deficient expression profile was very similar to that described during myeloid cell transformation 26 and breast tumours.

The need for glucocorticoid receptor dimerization to induce gene expression was further confirmed by transfection studies using wild type and glucocorticoid receptor dimerization-deficient expression vectors, indicating that transactivation of occludin occur through the GRE.

Using cells deficient in expression of glycosaminoglycans (GAGs) and short hairpin RNAs reducing heparan sulfate (HS) and chondroitin sulfate (CS) expression, we found that intracellular HS and CS (= GAGs) partly controlled the trafficking of CCL2 from the Golgi toward secretion.

Even if the relevant deficient gene expression level temporarily drops to zero, the disease state, represented by D, decreases again when gene expression rises.

Friedreich ataxia (FRDA) is a hereditary disease caused by deficient frataxin expression.