Sentence examples for deficient differentiation from inspiring English sources

All of these suggested adult MSCs had a deficient differentiation potential under mechanical strain.

Moreover, KAT5-Y47A mutant showed deficient differentiation rates (Supplementary Figure 5) together with decreased acetylation rates of SOX4 and SOX4 interaction compared with KAT5-WT.

Xist-deficient iPSCs exhibit increased expression of some X-linked oncogenes, abnormal growth rates and deficient differentiation potential relative to normal iPSCs.

We have also provided new data regarding the mechanisms how MSCs from adult rats displayed deficient osteogenic differentiation.

Therefore, it is unlikely that a deficient NCC differentiation is the sole cause for aneurysms in the aortic arch region.

As to the mechanism for the deficient osteogenic differentiation of MSCs from adult rats under mechanical stretch, we mainly focused on the role of ROS.

It is noteworthy that all the above developmental defects can be attributed to insufficient or deficient neuronal differentiation, suggesting the pivotal role of fezf2 in this process.

Sustained activation of Snail1 in transgenic mice provokes deficient osteoblast differentiation, which, together with the loss of vitamin D signalling in the bone, also impairs osteoclastogenesis.

These cell types have a far greater dependence on Th17 cytokines for their production of antibacterial peptides and chemokines, suggesting that the skin and lung infections in AD-HIES might be a result of deficient Th17 differentiation.

Previous studies have reported that ku70 −/− mice have decreased lymphocyte counts because of deficient lymphocyte differentiation caused by the absence of NHEJ-dependent T-cell and B-cell receptor maturation.

However, the expression of Cdx2 in ESCs was found to be rapidly initiated by Ras activation (i.e., within 24 hours) without previous or simultaneous downregulation of Oct4 expression [ 47], while ESCs with reduced Oct4 expression showed robust pluripotency and expressed naïve pluripotency genes, but were deficient in differentiation in the absence of pluripotency culture requisites [ 48, 49].