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Only a small minority of people suffer from diseases of or deficient development of the genitalia or that part of the neurophysiology governing sexual response.
This association is thought to be due to the collapse of the primitive fetal ventricular system (brought about by the loss of cerebrospinal fluid through the spinal defect), which prevents the rhombencephalic vesicle (from which the brainstem, fourth ventricle, and cerebellum are derived) from expanding and results in deficient development of the posterior fossa and herniation [38].
The observed Cho elevation may thus be interpreted as reflecting deficient development of the neurons.
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Taken together, our results show that both deficient development of T cells in the thymus and an abnormal antigen specific response in the periphery contribute to the phenotype of peripheral T cells in Foxn1Δ/Δ mice.
Abolition of visual input in animals during a critical period after birth can result in permanently impaired vision due to deficient development of visual processing in the brain.
These observations suggest that the deficient development of intracellular Δ isp2/3 is not linked to alterations in the ability to suppress macrophage activation.
Many children with DD show a deficient development of such a mental number line.
Problems with learning long behavioural sequences may ultimately lead to deficient development of verbally governed behaviour and self control.
In contrast, pre-immunocompetence systemic chimerism achieved in NK cell deficient recipients survives long after development of the recipient's immune system.
Interestingly, in Akt1 deficient mice, the growth and development of the placenta is impaired, resulting in IUGR, and it was proposed that fetal growth restriction was a result of placental insufficiency (52).
Thus, ineffective presentation of intranasal peptide in C1q- and C3-deficient mice could prevent the development of the antigen-specific CD4+ T cells expressing regulatory phenotype that are thought to be required for subsequent tolerance.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com