Sentence examples for deficient complement from inspiring English sources

The combination of the results of these three pathway activities allows us to speculate which candidate complement is deficient; subsequently, the deficient complement was determined.

The SNBPs of X. laevis consist of a structurally heterogeneous mixture of protamine-like proteins named SP1-SP6 that coexist with an H2A-H2B deficomplementlement of histones H3 and H4 [ 18].

Deficient complement-mediated IC handling increases the risk of extra-hepatic IC deposition and subsequent complement-mediated inflammation of the affected tissues [ 45].

Mice deficient in complement protein C1q or the downstream complement protein C3 exhibit large sustained defects in CNS synapse elimination, as shown by the failure of anatomical refinement of retinogeniculate connections and the retention of excess retinal innervation by lateral geniculate neurons.

These data were confirmed by in vivo experiments with mice deficient in complement component 5 (C6), C6 or the complement regulatory protein CD59a (Wang et al., 2011).

In particular, mice deficient in complement component C3, the lynchpin of the complement cascade, display reduced influenza virus-specific T cell responses in infected lungs, implying that complement activation plays an important role in T cell activation and/or recruitment [ 12].

Sprong T, Roos D, Weemaes C, Neeleman C, Geesing CL, Mollnes TE, et al. Deficient alternative complement pathway activation due to factor D deficiency by 2 novel mutations in the complement factor D gene in a family with meningococcal infections.

Studies of group B streptococcal infection in mice deficient in complement component C3 or C4 demonstrate an essential role for complement in both innate and acquired immunity.

Reduced tissue damage and improved recovery of motor function after traumatic brain injury in mice deficient in complement component C4.

We investigated the effects of cigarette smoke on nasal mucosa in vitro and via a model of cigarette smoke exposure by using animals deficient in complement components.

Mice deficient in complement components C3 (C3 -/-) and C4 (C4 -/-) were found to have a profound defect in their Ab response to a T-dependent Ag (bacteriophage (phi X174).