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The DNA damaging moiety augmented the potency in BRCA2 deficient cells by 2 20 fold.
M2-filamin A deficient cells were used as control.
Abrogation of JNK signalling prevents apoptosis in dVps4 deficient cells.
PRR5L knock down reduced apoptosis also in mTORC2 deficient cells.
Results with HIV PICs from BER deficient cells indicate that BER affects integration to naked DNA.
(E ) Reconstitution of α-SNAP deficient cells with α-SNAP.
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Open image in new window Figure 7 Phenotype of the IKKβ-deficient cells.
The inflammation response associated with cell senescence is significantly decreased in MAVS-deficient cells and mice.
Open image in new window Figure 8 Trak1 overexpression causes mitochondrial clustering in mitofusin-deficient cells.
Rhou-deficient cells in embryoid bodies also display abnormal epithelial organization.
Mgmt-deficient cells are hypersensitive to the killing action of dacarbazine.
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