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Lissoclinotoxin F showed a threefold higher cytotoxicity against the PTEN deficient cell line.
On the other hand, the DNA PKcs deficient cell lines showed efficient double-strand break repair by both mechanisms.
p53ΔP exhibited increased sensitivity to Mdm2-dependent degradation and decreased transactivation capacity, correlating with deficient cell cycle arrest and reduced apoptotic responses.
The isopropyl carbamate derivative 34 was identified as a highly chemoselective agent displaying a potency of 51 nM in the p21 deficient cell line.
Pre-integration complexes from BER deficient cell lines show reduced integration activity in vitro.
Identical camera and microscope settings were employed to allow valid comparison between images of control and macroH2A1 deficient cell populations.
Similar(33)
Many investigators have noted deficient cell-mediated immunity in advanced cancer patients.
Deficiency in Bim and, to a lesser extent, Bax partially rescued Mcl-1-deficient cell survival in RPMI.
This method provides advantages over previously reported methods to create Mgat1-deficient cell lines.
The interaction of PEX3-EYFP with ECFP-PEX19 in a PEX3-deficient cell line during peroxisome biogenesis was visualized by FRET imaging.
TEPW transduction led to a complete surface expression of the GPI anchor and CD59 in PIGA-deficient cell lines without any selection procedure.
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