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Briefly, a clinical diagnosis of NC 21-hydroxylase deficiency was established on the basis of late-onset symptoms of androgen excess, elevated basal 17-hydroxyprogesterone (17OH-P) (>2 ng/ml), and an abnormal -at least three-fold the upper limit of normal- 60 minute 17OH-P response to Synacten stimulation (>10 ng/ml).
In the twin girls, a diagnosis of complex I deficiency was established on muscle biopsy respiratory chain enzyme analysis.
The relationship between age and severity of vitamin D deficiency was established by Knutsen et al. [ 33].
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Transient transfections of these plasmids into the hMLH1−/− background were performed to verify their EGFP expression in cells and detected by a fluorescence microscope before stable cell lines with different MMR deficiency were established.
The ultimate mechanisms by which DC deficiency is established are not understood.
IgG subclass deficiency is established when one or more IgG subclasses are 2 SDs below the age-adjusted reference range, along with normal total serum IgG levels.
PACE4-knockdown associated growth deficiencies were established on the knockdown HepG2, Huh7, and HT1080 cells as well as the antiproliferative effects of the multi-Leu peptide supporting the growth capabilities of PACE4 in cancer cells.
Growth hormone deficiency length was established from 8too 384 months (mean value 154 ± 115 months).
Diagnosis of GLUT1 deficiency (G1D) was established and a ketogenic diet (4:1 ratio, containing medium chain triglyceride oil) was initiated (CoQ treatment was then discontinued).> -wrap-foot> Patient results from blood are expressed as range (median).
In the absence of a gold standard to define functionally iron deficiency in pregnancy, was established as the reference standard the haematological response to oral iron-therapy, which is considered a reliable and low-cost alternative for the confirmation of anemia due to iron deficiency [ 1].
Although, the first cases were reported in 1937 during an epidemic in a rural area of China called Keshan, hence the term Keshan Disease [ 60], it was not until 1971 that a correlation between selenium deficiency and this disease was established.
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