TGF-β enables the tumor to efficiently evade immune surveillance by potently suppressing the maturation and function of DCs, which leads to a deficiency in antigen presentation and immune response (Grauer et al., 2007).
In a letter to Peter S. Kalikow, the M.T.A. chairman, Mr. Thompson wrote: "While the glaring deficiencies in the M.T.A.'s presentation of the T.A.'s budget proposal may not constitute a breach of the M.T.A.'s fiduciary responsibilities, it does constitute a breach of responsibility to the citizens of New York City".
A deficiency in the area of professionalism is taken as seriously as a deficiency in cognitive knowledge.
(Some researchers implicate omega-3 deficiency in rising rates of depression and learning disabilities as well).
Congenital adrenal hyperplasia due to 21-hydroxylase deficiency is the most common presentation of a disorder of sex development (DSD) in genetic females.
If a fetus is homozygous or compound heterozygous for the deficiency, there may be a presentation of purpura fulminans, severe disseminated intravascular coagulation and simultaneous venous thromboembolism in the womb; this is very severe and usually fatal.
It is thus likely that the previously reported cross-presentation deficiency in ΔY-derived DCs resulted from the inability of these tyrosine-mutated surface Kb molecules to traffic through endocytic loading compartments (ELCs) [21].
However, it is of note that there is a substantial variability in the clinical presentation of patients with combined pituitary hormone deficiency even if the same gene is affected and even in subjects with identical mutations.
We have previously described the adult presentation of H6PDH deficiency in three females (4).
TRPV1 knockout mice showed no deficiencies in their ability to detect an acute presentation of eugenol in the cotton swab assay.
(We should remark that some authors also consider − | x | + | r | and call this the deficiency of the presentation P.) Remark 1 In both group and monoid cases, if the presentation P in (1) is efficient or inefficient while it is minimal, then it always has a minimal number of generators.
