For example, it would be important to know whether breast cancer cell lines with EMSY amplification display some of the phenotypes (radiosensitivity and deficiency in homologous recombination) characteristic of BRCA2 null cells.
The fresh mass of roots and size of the root were the parameters most negatively affected by the use of SASC, sharply decreasing with the addition of SASC, which may indicate a deficiency in the physical characteristics of the SASC.
The altered carbon metabolism could then cause a deficiency in general plant growth characteristics such as coleoptile length [ 23].
Microsatellite instability due to a deficiency in DNA mismatch repair is characteristic of a replication error (RER) phenotype.
Our findings thus suggest that IR, rather than deficiency in insulin secretion, is a characteristic of individuals reporting more frequent sleep complaints.
These cells also exhibit stem cell characteristics, including deficiency in GJIC [ 7], capacity for anchorage-independent growth (AIG) [ 13], ability to differentiate into basal (type II HBECs) and luminal (acini-forming) epithelial cells [ 7, 13], expression of the embryonic stem cell marker Oct-4 [ 3], and the ability to form budding/ductal structures on Matrigel [ 13, 14].
Notably, there were >9-fold increases in GC→AT and AT→GC transitions, characteristic of a deficiency in mismatch repair.
In both disorders, there is a lack of development of secondary sexual characteristics and some deficiency in libido and potency.
We previously reported that reduction of TR1 levels in cancer cells reversed many malignant characteristics suggesting that deficiency in TR1 function is antitumorigenic.
Some disagreement persists as to the characteristic syndrome of riboflavin deficiency in humans because it tends to be associated with a deficiency of other vitamins, notably niacin (see pellagra).
Loss of mitochondrial DNA (rho− and rho° cells) is a characteristic phenotype of frataxin deficiency in yeast cells (17– 17).
