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Activities for control by health workers entail interventions for systemic conditions (measles, vitamin A deficiency), identification and referral of children with sight threatening conditions and health education for caregivers.
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To alleviate this deficiency in identification that would have adverse effects on lower abundance proteins with suboptimal quality product ion spectra, the algorithm represented by the blue curve represents a practical compromise.
This results in deficiencies in identification of fire hazards and undermines any attempt at design optimisation.
Considering that these children usually have other pituitary hormone deficiencies, early identification of these cases may prevent complications.
To describe two cases of 5α-reductase deficiency and the identification of a novel frameshift mutation in this sibling pair.
This aCGH platform is attractive as it allows detection of genomic instability resulting from HR deficiency without requiring identification of the precise molecular etiology.
However, pleiotropic phenotype derangements induced by calreticulin deficiency challenge the identification of specific downstream transcriptome elements that direct proper cardiac formation.
A recent report by Gayther et al [ 3] takes a significant step in rectifying this deficiency, with the identification of truncating mutations of p300 being associated with mutation of the second allele in both tumour samples and cell lines.
A more detailed analysis of Zone 1B highlights the value of applying the physical deficiency map to the identification of uncloned mutations.
The availability of a biomarker for MSH2 deficiency should enable the identification of patients who would possibly benefit from methotrexate treatment.
Nevertheless, due to the potentially fatal consequences of ignoring TPMP deficiency [ 47], the identification of such individuals and of the about 10% of heterozygous carriers is recommended, even in the drug label [ 48].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com