In order to confirm that the respiratory deficiency was attributable to the mt-tRNAval mutation, we transfected the respiratory deficient T1 line with VARS2 (designating it T1V1) and monitored growth on galactose.
For example, it would be interesting to hypothesize whether there is any phenotype reported for miR-155 deficiency actually attributable to loss of miR-155*.
To address whether resistance to DSS-induced colitis conferred by IL-25 deficiency was attributable to a defect in IL-13 expression, we exposed IL-13−/− mice to DSS for seven days.
The present study therefore provides evidence that some of the metabolic phenotypes of Txnip deficiency may be attributable to its regulation of UPR signaling.
In her dissent, Judge Susan Phillips Read cautioned that "educational deficiencies are not always attributable to the lack of money or necessarily cured by the infusion of more funds".
All methods fail grouping Thermotogae with Proteobacteria, a deficiency that might be attributable to the absence of other organisms from the dataset.
This same author had indicated that increased translation may be attributable to deficiency of ribosome degradation, rather than de novo ribosome synthesis [ 76].
Vitamin B-12 deficiency, which is frequently attributable to age-related gastric atrophy, is relatively common in later life and affects about one-sixth of people aged >75 y in the United Kingdom (1).
Although the ultimate cause of the severe fertility impairment proved to be a widespread preimplantation arrest at the 2- to 4-cell stages, the embryos were already abnormal at the 2-cell stage, with a marked deficiency of polar bodies attributable to frequent failure of the second meiotic division.
For example, mitochondrial iron overload is a distinctive feature of the heart and some neurons of FRDA patients (Koeppen, 2011), of the skeletal muscle cells of individuals with ISCU myopathy (Mochel et al., 2008), and of the immature red blood cells of a patient with sideroblastic anemia attributable to deficiency of GLRX5 (Ye et al., 2010).
