Sentence examples for deficiencies of brain from inspiring English sources

Medication has often been thought as type 1 or type 3 interventions, but there is as yet little evidence that deficiencies of brain monoamines actually cause depression.

It has been hypothesized that alcohol-preferring rats have impaired control over consumption of reinforcing substances, which may be related to a deficiency of brain serotonin.

Deficiency of brain thyroid hormone production contributes to reduced central serotonin activity and development of depression [ 6, 12].

One young adult (subject 9) had biochemical evidence over 5 years of a progressive deficiency of brain dopamine but without clinical features of Parkinsonism.

Investigators now understand that narcolepsy arises from a deficiency of the brain cells that make hypocretin, similar to the way that Parkinson's is caused by the loss of dopamine-producing neurons.

Thyroid hormone deficiencies during critical periods of brain development result in profound structural as well as functional abnormalities (1– 4).

Cerebral glucose metabolism, measured using positron emission tomography scanning, was reduced by insulin deficiency so that ∼20% of brain glucose uptake is insulin influenced, with lesser effect in individuals with peripheral insulin resistance (46).

Our present and previous findings indicate that the following chain of events takes place during NPSLE: intrathecal release of inflammatory cytokines, leading to synthesis and release of MMP-9, potentially culminating in insult to brain parenchyma, resulting in release of neuronal and astrocytic degradation products and culminating in MRI verifiable lesions and clinical states of brain deficiency.

Therefore, the potential effect of aging and estrogen deficiencies on the lipid environment of brain and γ-secretase activity warrants investigation and may provide insight into the gender specific γ-secretase activity differences in aged brain we observed.

The relative deficiencies of the preclinical AD brain may be seen as mimicking the mental faculties of a lower primate.

Patients affected by cerebral creatine deficiency syndrome-1 (CCDsharehare depletion of brain Cr and the clinical phenotype with patients carrying the other two defects of Cr metabolism which involve mutations of genes encoding the biosynthesizing enzymes AGAT and GAMT (Item et al., 2001; Stockler et al., 1994).