Firstly, copper deficiency, in addition to causing neurological dysfunctions, also results in haematological abnormalities, most commonly neutropenia and anaemia [ 97].
14 Thus, estrogen deficiency, in addition to directly increase bone resorption, may result in a negative calcium balance due to an impaired calcium absorption from the gut and to an increased renal calcium excretion.
According to Morris et al, 94 considering the scarce scientific literature on this topic, it would be safer to avoid folic acid supplementation in case there is no evidence of a clear deficiency, in addition to a continued monitoring of vitamin B12 deficiency.
Analysis of the phenotype of the C. reinhardtii psr1 mutant grown under Pi-deficiency showed that in addition to altering the normal acclimation to Pi deprivation, the psr1 mutant had a de-repressed sulfate deficiency response, leading to overexpression of genes involved in sulfate scavenging and assimilation [ 41].
The deficiencies of existing models in addition to the complexity of resilient behavior of soils indicate the necessity to develop better models.
The deficiencies associated with DSE in addition to D4ST1 affect the biosynthesis of DS, which implies that both enzymes are essential for the development of skin and bone as well as the maintenance of their extracellular matrices.
Only in Sandhoff disease oligosaccharides derived from glycoproteins accumulate due to the deficiency of β-hexosaminidase A in addition to the (functional) deficiency of β-hexosaminidase B [ 13].
In cases of an elevated serum CA15-3 level without apparent breast cancer recurrence, pernicious anemia due to vitamin B12 deficiency should be considered in addition to other malignancies.
However, in the treatment of severe maxillary retrognathism, it is necessary to reconstruct areas of bone deficiency through grafting techniques in addition to maxillary advancement using only the Le Fort I osteotomy.
We screened P-element lethal as well as deficiency collections for interactors in addition to performing a classical ethylmethanesulfonate (EMS) screen for dominant modifiers.
