In contrast, as the defects of this study, the follow-up examination is relatively short.
As a result, no definite conclusion could be reached because of the design defects of the included studies and the small number of studies analysed in the meta-analyses.
This defect of the study has to be corrected in future well-planned studies.
However, it was not possible to obtain uniformity in the subsample sizes according to age, consistent with our study design, and a major defect of the study was our failure to sample individuals < 17 years old, because the samples were obtained with the voluntary participation of the population, and if children are included, the consent of their parents is legally required.
Although a systematic review of acupuncture for neurogenic bladder after SCI was published in 2013, the result of the review was inconclusive due to the serious methodological defects of the included studies and the small number of trials assessed in meta-analyses.
These results were mirrored in the untreated chondral- and osteochondral defects of the present study as seen in Table 2 and Fig. 3a and b.
However, the defect of this study was the lack of an orthotopic human pancreatic cancer xenograft animal model to evaluate the in vivo contrast enhancement imaging efficacy of the CXCR-4-USPIO probe, and this issue will be our research direction in the future.
In addition, detailed information about recurrence was not available, which is a defect of this study, making the investigation of the relation between SDF-1 expression and recurrence unachievable.
An American biostatistician attempted to avoid the defects of genealogical studies by collecting records of the family histories of 365 nonagenarians (90-year-old persons) and of a comparison group of 143 individuals of varying ages, selected because all of their six immediate ancestors were dead.
There was no observed change in severity (average dB loss) for the central defect of the 17 study participants who had a central defect at both baseline and randomization (mean 11.5dBB versus 6.7 dB at baseline and randomization, respectively; p = 0.09) after SFC adjustment.
