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Unfilled defects of the same size on the contralateral sides of the mandibles served as empty controls.
Keeping a history of defects, their means of detection, containment, isolation, and recovery will certainly help in mitigating future defects of the same type.
Phenotypic analyses of patients with such reciprocal CNVs have revealed instances in which the phenotype is either identical or mirrored; strikingly, molecular studies have shown that such phenotypes are often driven by reciprocal dosage defects of the same transcript.
We extend this analysis as well to defects in Moiré patterns, which have been reported recently, and which are the result of defects of the same symmetry in the constituent 2D material layers.
Real-time RT-PCR analyses showed significantly lower expressions of Alpl, Col1a1 and VEGFA in cranium defects after treatment with PHB patches compared to untreated bony defects of the same cranium.
Although it appeared possible to create defects of the same size, the bone architecture in the defect region varied from one rat to another.
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Slit-lamp examination of the right eye showed a well-defined, dense, whitish infiltrate in the central cornea with an epithelial defect of the same size.
One example is of a 'tubular' visual field defect, where patients with a functional loss of their central visual field report a defect of the same diameter, whether it is mapped close to them or far away.
To demonstrate this, in one of our next studies we will take muscle tissue from a rat, genetically modify the tissue fragments intra-operatively and re-implant the gene activated tissue into a bone defect of the same rat.
When mutants of differing TSS shift class have been combined (Sun and Hampsey 1995; Ghazy et al. 2004; Freire-Picos et al. 2005; Kaplan et al. 2012), they generally exhibited mutual suppression of TSS defects coupled to suppression of growth defects, whereas mutants of the same class exhibited enhancement of TSS and growth defects.
The patients had combined acetabular defects (type III, AAOS) and were analyzed mean 7 years after the same type of revision THA, including impaction grafting and restoration of segmental defects by the same kind of perforated plate.
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