Sentence examples for defects in the generation from inspiring English sources

Ezrin−/− mice also showed no defects in the generation of double positive T cells (Figure 8C).

In order to define the role of antibodies, we used several mouse strains with individual defects in the generation or functioning of antibodies.

We also performed competitive mixed bone marrow chimeras, and under these conditions Egr-2-/ thymocytes have very profound defects in the generation of iNKT cells (data not shown).

In contrast, when Fyn levels were reduced, thus augmenting γδTCR signal strength, we observed defects in the generation of both IL-17- and IFNγ-producing effectors.

For instance, some defects in the generation and function of DA neurons are obviously part of the Parkinson's disease phenotype but have also been reported in Alzheimer's disease.

Preliminary data do not indicate any difference in cytorrhysis between appressoria formed by ΔpdeH mutant and wild-type strains (data not shown), suggesting that appressoria of ΔpdeH mutants do not have defects in the generation of turgor pressure.

We can exclude that this defective orientation results from a defect in the generation of planar polarity cues at the clone border since both fz RNAi) (Fig. 4B,B') and Vang mutant SOPs (Fig. 4D,D') appear to orient their polarity axis relative to the border of the Vang and fz RNAi) clones, respectively.

A deficiency of these genes results in a defect in the generation of secondary lymphoid structures (Tachibana et al., 2011).

X-linked agammaglobulinaemia (XLA) is a genetic disorder characterised by a defect in the generation of mature B cells, lack of antibodies production, and susceptibility to recurrent bacterial infections.

As shown in Figure 1B, while reduced number of CD8+IFNγ+ T cells was observed in IL-15 deficient mice, IL-7 depleted WT mice did not exhibit a defect in the generation of this population.

Whether this is due to a defect in the generation of endothelial progenitors or to an inability of these cells to be released into the circulation is still unknown.