Sentence examples for defects in the dermal from inspiring English sources
Several human pigmentation disorders such as ceruloderma, a type of dermal melanosis, and forms of post-inflammatory hyperpigmentation are due to defects in the dermal layer, indicating that human pigmentation is indeed not exclusively regulated in the epidermis, but also in the dermis (Ortonne 2012).
We found that IL-22−/- mice displayed major defects in the skin's dermal compartment after full-thickness wounding.
To investigate if defects in the BM contribute to the disease mechanism, dermal biopsies were collected from a patient (IV:21 in Fig. 1A), his unaffected father, who carries the mutation (III:8 in Fig. 1A), and an ethnically matched control.
Because of the defect in the continuity of the dermal connective tissue, these striae are soft to the touch.
It's synthesised from testosterone by an enzyme, 5-alpha-reductase, that's found in the dermal papilla, a small compartment at the base of the hair follicle.
Dermal papilla cells sustaining intrinsic hair inductive capacity, putative dermal papilla precursor cells in the dermal sheath/neonatal dermis or trichogenic dermal cells derived from undifferentiated stem/progenitor cells are promising candidates as hair inductive dermal cells.
In physiologically normal human skin, SDF-1 is constitutively and highly expressed in the dermal fibroblasts.
Defects in the dermal epidermal junction in the AEC mouse skin were not observed at the histological level or in EM studies, in spite of the known role of p63 in regulating expression of a number of integrins, and hemidesmosome and extracellular matrix components (2, 10, 65, 66).
