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Atomic scale computer simulation of a model of the h.c.p. metal α-titanium is used to investigate the mobility of interfacial defects in response to applied shear stress.
Nevertheless, extracellular KS may also be affected, secondary to amelioration in KS turnover and trafficking defects, in response to lysosomal clearance by rhGALNS.
In contrast, both egl1 ctf7 and rad24 ctf7 double mutant cells exhibited synergistic growth defects in response to MMS (Figure 6).
Mice deficient of FHL2 display defects in response to divers stimuli, including cardiac hypertrophy under β-adrenergic stimulation, healing defects in skin and intestinal wound and attenuated neovascularization after corneal injury [19] [22].
Studies of isolated islets show that insulin release defects in response to glucose are associated with impairments in KATP channels and intracellular calcium flux [ 31].
In both human and mouse studies, for example, there is considerable individual and strain variation in enamel defects in response to a standardised fluoride intake.
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Tissue culture was performed in vitro by placing a CP-Ti plate in a cultured rat neonatal calvarial defect in response to ultrasound stimulation.
However, it cannot be excluded that the enhanced tissue repair is derived from host cells recruited to the defect in response to the implant, rather than the re-population of the tissue by the implanted MSCs.
At best, ctf7 mutant cells exhibited a very modest growth defect in response to MMS.
These results therefore identify a role for PKCε in the GPVI signalling pathway that is mediated by a reduction in phosphorylation of the FcRγ-chain underlying the selective defect in response to collagen and CRP.
In Ba spores, impairment of GerPF expression causes a germination defect in response to nutrient germinants [ 85].
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