Sentence examples for defects are manifested from inspiring English sources

Thus, differentiation defects are manifested early at the genomic level leading to aberrant transcription of the genes involved in differentiation along the neuronal lineage.

These defects are manifested by the activation of the unfolded protein response (UPR) that involves the transcriptional up-regulation of several ER resident proteins, the down-regulation of protein translation and up-regulation of ER associated degradation (ERAD).

The resulting neurological disturbances and developmental defects are manifested over the entire lifetime of the offspring and are referred to as fetal alcohol effects or fetal alcohol syndrome (FAS), depending on their severity.

According to NKNews "Defects were manifested in the last phase of the construction of the Terminal 2 because the designers failed to bear in mind the party's idea of architectural beauty that it is the life and soul and core in architecture to preserve the Juche character and national identity," Kim said in comments reported by KCNA.

The results are assumed to originate from the Sb intermixing in the GaAs matrix, with varied compositions, stresses, and defects being manifested in the GaAs IF signal.

To understand how these secretory defects are manifest in an islet we exploited a two-photon assay to measure single-granule-fusion events within the core of intact islets of Langerhans [ 24], where almost all the cells in rodent islets are beta cells.

In cases where severe proliferative defects were manifest, cells were harvested at the point where the proliferation defect was beginning to become significant.

Dorsal closure defects were manifest with a conspicuous hole in the dorsal cuticle.

Selective ablation of myosin IIB resulted in polarity defects which are manifested phenotypically as the inability of blastopore and neural tube closure [39], [40].

Because the proteolytic defects of npl4-1 are manifested at the semi-permissive temperature of 30°C (Bays et al., 2001), we carried out the experiment in Figure 1B at 30°C.

Genetic defects in the DNA structure that are manifested as defective sequences of DNA bases in the same DNA strand can lead to defective protein synthesis.