Exact(23)
The affected members of the London family in which the defective version of FOXP2 was discovered do possess a form of language.
Mice with a defective version of this gene were able to remember tasks better than those with the normal variation, according to an article in the Guardian.
Women with a defective version of a tumour-suppressing gene called BRCA-1 are much more susceptible to breast and ovarian cancer.
A defective version of a gene called RPE65 means that, in this condition, retinal cells are starved of vitamin A, which also causes blindness.
And so to treat a disease like sickle cell, converting the defective version of the gene back into the exact healthy copy, and doing so with an efficiency that is clinically useful, is still very difficult.
In 1990 scientists identified a gene on human chromosome 17 that is responsible for neurofibromatosis type 1; a defective version of this gene allows nerve cells to grow without restraint, resulting in neurofibromas.
Similar(37)
One of Helleday's projects focuses on cancers caused by a rare defect in a tumor-suppressor gene; women with defective versions of the gene have up to an 80% increased risk of breast or ovarian cancer.
It is shown that tubes are formed by structurally defective versions of conical graphene layers.
Defective versions of BRCA1 and its sister gene BRCA2 are together responsible for about a fifth of breast cancers.
Some of the mice also had defective versions of the tumor suppressor gene p53, which is mutated in about half of human lung cancers.
The defective versions of the gene encode proteins that cannot recognize these messages, in effect cutting the cell off from essential directives, including perhaps messages that promote wakefulness.
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