Sentence examples for defective utilization of from inspiring English sources

These abnormalities point to a defective utilization of iron for biosynthetic processes taking place in the mitochondria, in particular ISC synthesis.

This shortened period of placental maturity relative to the gestational period could render the mouse placenta particularly susceptible to stress induced by defective utilization of nutrients and/or impaired calcium metabolism in the context of mitochondrial dysfunction.

Finally, the ΔarcA strain was defective in utilization of DMSO only, as reported elsewhere [13], [21].

70 However, CD36 knockout mice do not have any apparent skin phenotype, while defective uptake and utilization of LCFA have been reported in muscles and adipose tissues.

In summary, these results suggest that 3-hydroxybutyrate does not modulate HIF-1α expression or activity in the glioma cell lines analyzed, and therefore provide additional evidence for a defective ketone body utilization of glioma cells.

As a consequence, although the empirical vibration levels suggested by the standard are helpful in ensuring the safe operation of a bearing, they cannot guarantee full utilization of the residual life of a defective bearing.

Finally, we obtained further characterization of the defective ATP utilization produced by the invariant His mutation (H479Q), analogous to those involving the human copper ATPase (ATP7B) in Wilson disease.

Although the cause of anemia in heart failure is unclear, the weight of evidence suggests that renal dysfunction, along with neurohormonal and proinflammatory cytokine activation in heart failure, favors the development of anemia of chronic disease, with defective iron utilization, inappropriate erythropoietin production, and depressed bone marrow function.

Renal dysfunction, neurohormonal activation, and proinflammatory cytokines in heart failure enable the development of anemia of chronic disease, with defective iron utilization, inappropriate erythropoietin production, and depressed bone marrow function [ 19].

It is of interest that defective ATP utilization is produced by a histidine residue mutation (H479Q) in the bacterial T. maritima CopA, in analogy to that produced by the corresponding mutation in human Wilson disease copper ATPase (ATP7B) [ 34].

A high-fat diet induces the suppression of HSL and AMPK signaling in lipolysis and the utilization of lipids in visceral and subcutaneous adipocytes, which may play an important role in the defective lipid mobilization and metabolism observed in diet-induced obesity [ 56].