Sentence examples similar to defective up from inspiring English sources

CD19-deficient human B cells displayed defective up-regulation of activation markers after TLR7/9 triggering and failed to induce BTK, AKT but not p38 MAPK or Iκ-Bα phosphorylation after TLR7/9 stimulation.

Preliminary studies from our laboratory suggest that in absence of both of these cytokines there is defective up-regulation of master transcriptional factors, T-bet and Eomes in CD8+ T cells (Figure S5).

In the case of schistosome egg antigen, this effect is due to omega-1, a glycoprotein which degrades intracellular host RNA, resulting in defective up-regulation of T cell-activating inflammatory cytokines such as IL-12 89.

The ProC® Global is a clotting assay designed to globally evaluate the functionality of the protein C (PC) pathway, which is found defective in up to 30% of the Caucasian patients with thrombophilia.

A component of the regulatory machinery could be defective in UP cells, but we find it more likely that the concentration of the sensed cytosolic Fe species used in regulating Fe import was significantly below the threshold concentration in CCC1-up cells, even when grown on [Femed] as high as 40 μM Fe.

"They had to send me several new locks (some of the new stuff was also defective) to get up and running initially.

By gobbling up defective mitochondria, lysosomes may make cells less likely to damage their DNA.

Moreover, your shopping rights under the Sale of Goods Act entitle you to claim redress for inherently defective goods for up to six years.

C1 Business Digest C1 CIRCUITS G1-14 ARTS E1-12 HOUSE & HOME F1-16 EDITORIAL A30-31 Editorials: The Bush prescription drug plan; Congress takes up defective tires; for Assembly and Civil Court judge.

But how this DNA winds up defective to begin with is mysterious.

Perhaps pessimism on JNJ stems from the continuing – and now expanded – investigation into drug manufacturing at the firm following the “phantom recall” wherein, allegedly, Johnson & Johnson hired contractors to buy up defective Motrin tablets in stores rather than issue an immediate formal recall of the medication.