Sentence examples for defective selection from inspiring English sources

We do not support such possibility, since we are not aware of any report indicating that mouse strains with defective selection defects in the thymus are prone to tumorigenesis in the T cell compartment.

To engineer recombinant yeast that stably maintains expression cassettes without an antibiotic resistance gene, we developed new multiple integration cassettes by exploiting the non-transcribed spacer (NTS) of ribosomal DNA (rDNA) in combination with defective selection markers.

These advantages include its ability to metabolize acetate, glucose, alcohols and hydrophobic substances such as alkanes, oils and fatty acids, resembling mammalian system of glycosylation, well characterized secretory systems yielding high levels of recombinant proteins (i.e. 2 g L−1) using defective selection marker, easy screening of multi-copy strains and single integration site usage.

There are essentially two anomalies affecting folliculogenesis [ 23]: excessive small follicular growth and the defective selection of a dominant follicle.

In contrast, in the pINA1297/pro-TGase pINA1297/pro-TGasestion liberates a "yeast cassette" devectorf bacterial DNot bordered by zeta sequences and contaIning the ura3digestionive seliberatesarker.

As the development of thymocytes in CD4-FADD mice remains intact, the increased apoptosis in DP cells may not lead to the severe arrest in Lck-mice, suggesting the defective survival signals in β-selection is a main reason for the decrease of DN4 cells.

This defect has been previously attributed to a defective positive selection that leads to enhanced mortality rates in this thymic subpopulation [21].

Many theories for the induction and maintenance of such responses have been entertained including molecular mimicry between HIV proteins and self molecules, CD4+ T cell loss accompanied by loss of normal immune regulation that dictate self non-self-reactivity, defective negative/poself non-self-reactivityllself non-self-reactivity

Finally, the concept of defective embryo selection explains why some RPL patients appear to be exceptionally fertile.

We previously demonstrated that Rhoh-/ mice have impaired TCR signaling, resulting in defective thymocyte selection and blocked maturation of T cells[3].

It has been shown that Egr-2 deficiency results in impaired NKT cell development and defective positive selection of T cells.