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TAF4 inactivation in early post-natal hepatocytes led to defective liver organisation and function resulting in death of the animals by P15.
It stands to reason that liver transplant would not replace defective BSEP in the other cells of the body, despite normal liver function.
In light of the susceptibility of L2AKO mice to stress-induced loss of protein homeostasis, we set out to comparatively analyze the impact of aging on liver function, metabolic regulation, and proteostasis in Ctr and CMA-defective animals.
Similar results were seen at many other post-natal activated liver function genes indicating that loss of their expression in Taf4ahep −/− liver corresponds to defective PIC formation in the absence of TAF4.
Their liver function test results improved.
Will her kidneys and liver function normally?
A 7-year-old boy urgently needs a transplant because of a defective liver.
They include: Kidney and liver function.
A routine exam showed abnormalities in liver function tests.
Despite Mr. Yeltsin's reputation for excessive drinking, his liver function was normal.
His liver function declined, he was placed on dialysis and was breathing through a respirator.
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