Sentence examples for defective integration from inspiring English sources

Here we propose that this impairment arises from defective integration of mediotemporal 'what' and 'where' routes, carrying object and spatial information to the hippocampus.

Consequently, mutations in this region may cause defective integration of dimers into the thick filament leading to accumulation of unassembled MyHC.

The high incidence of the dysmotility disorders emphasizes the defective integration and modulation of information in the brain gut axis in CP [ 30, 34, 35, 41, 43, 49], for which some investigators had proposed the term "Dysphagia GOR complex" with a central role for the vagal nerve [ 33, 34].

Impaired ability to distinguish the effects of one's own from others' actions might therefore potentially result from impaired prediction coding in the cerebellum or defective integration of sensory percepts by the thalamus or the parietal or prefrontal cortex [ 5, 7, 17].

In this Review, we have considered current therapies where either the presence or absence of positional information could cause defective integration phenotypes, and have discussed molecular tools that could be used to manipulate the positional information in cells, as well as their ability to communicate this positional information in future cell-based therapies.

These results demonstrated that an early protective immunity against WNV was achieved with a single administration of lentiviral vector defective for integration.

As such, lentiviral vectors defective for integration could supersede their integrating counterparts in clinical purposes that target postmitotic cells.

In large part, work with other animal models has expanded upon studies in the dt rat and shown that primary dystonia is a multi-nodal network disorder associated with defective sensorimotor integration.

Formation of circular DNA is a result of accumulation of viral cDNA and is indicative of a defective HIV integration into host genome.

It is also possible that a defective sensori-motor integration might reflect a disrupted "binding mechanism", i.e. the process responsible for associating visual and sensori-motor information related to the self to semantic information pertaining to the action [47].

This result suggests that Gαo-mutant females are not entirely unresponsive to estrus-modifying pheromones but the functional outcome of such chemosignals is altered, perhaps as a result of defective processing or integration with other pheromonal cues.