Sentence examples for defective growth from inspiring English sources

RASopathies, a family of disorders characterized by cardiac defects, defective growth, facial dysmorphism, variable cognitive deficits and predisposition to certain malignancies, are caused by constitutional dysregulation of RAS signalling predominantly through the RAF/MEK/ERK (MAPK) cascade.

The authors suggested that defective growth regulation could not be the primary defect in the initiation of cysts, but rather the relationship between proliferation and cyst formation might be indirect.

The authors observed a defective growth of stromal progenitor cells in colony-forming unit fibroblasts, a defect in sinusoidal endothelium, and the loss of stromal cells expressing CXCL-12 or IL-7 in the bone marrow.

The loss of α-catenin expression and subsequent defective growth control observed in many cancers may therefore be mediated through dysfunction of this novel α-catenin SRF pathway.

Rickets is a disorder secondary to deficiency of vitamin D. The major consequence is bone disease, with defective growth of the epiphyseal cartilage.

Something similar happens in animal systems, when virus-infected cells or cells with defective growth control that could become cancerous undergo programmed cell death," he says, noting that aspirin has been found to have a protective effect against cancer.

The optimal additive amount of DIO could contribute to a more uniform and non-defective growth of perovskite crystal nucleation, enabling preparation of the smooth and compact film with large grain size.

Taken together, high-sugar-fed larvae demonstrate criteria for a model of T2D: hyperglycemia, insulin resistance and insulin-defective growth phenotypes.

A deficiency of Chk2 partially rescued the defective development and growth of BRCA1 deficient T-cells but enhanced tumour development.

The decreased TLC and forced vital capacity may be due to cardiac enlargement or to defective pulmonary growth secondary to reduced growth of the thoracic cavity.

These experiments showed that inadequate amounts of the megaplasmid ParAB proteins lead to genome segregation and/or replication defects and provoke defective cell growth.