Sentence examples for defective explanations from inspiring English sources

Although resistance is logically futile, the resentment persists and is rationalized by defective explanations, since the alternative is emotionally unacceptable.

His basic strategy is to attempt to show that the derivations we regard as good or acceptable explanations are instances of patterns that taken together score better according to the criteria just described than the patterns instantiated by the derivations we regard as defective explanations.

This demonstrates that the cohesion establishment factors studied in this experiment contribute to cohesin acetylation during DNA replication, offering a possible explanation for defective sister chromatid cohesion in their absence.

An alternative explanation for the defective accumulation of the above mutant neutrophils at the site of inflammation is defective release of neutrophil-derived pro-inflammatory mediators, leading to defective generation of an inflammatory, chemoattractant environment.

One possible explanation might be defective Ca2+ homeostasis in FB1-treated Atgl /– macrophages as revealed by substantially higher basal cytosolic Ca2+ levels compared with Wt macrophages.

Importantly, we described that persistent T. gondii infection particularly affects cortical neurons, manifesting changes in morphology and dendritic bundling, therefore providing a possible explanation for the defective connectivity described by DT-MRI.

Thus, one explanation for the defective Le- cre; Wls fl/fl optic cup is that a Wnt signal from surface ectoderm normally elicits a response in the optic cup rim that helps to shape the structure.

Subsequently, a prolonged life span of FLSs was recognized (reviewed in [ 68, 69]), although even a combination of enhanced proliferation of the normally slow growing FLSs plus defective apoptosis seems an insufficient explanation.

The most straightforward explanation for how defective mitochondrial fusion or fission can adversely impact mitophagy is that an intact fission fusion cycle is essential for asymmetric mitochondrial fission in which damaged or malfunctioning mitochondrial components are segregated from healthy components and targeted for removal (Twig et al, 2008; Dorn, 2015) (Fig 5).

Interaction at these levels producing defective organ formation could provide an explanation for the diminished survival of Sdc4 Vangl2 compound mice.

One possible explanation for the involvement of defective autophagy in Crohn's disease inflammation couples the risk alleles in ATG16L1 and NOD2 (nucleotide-binding oligomerization domain containing 2) to an impaired clearance of microorganisms [20], [21].