Sentence examples for defective establishment from inspiring English sources
Mutations in the microtubule-associated MID1 protein lead to defective establishment of these structures and the development of the ventral midline disorder OS [3].
In mice, absence of ZFP57 also results in defective establishment of maternal methylation at the imprinted Snrpn locus [3,5].
Thus defective establishment of the left right axis in integrin α5-null mutants (Pulina et al., 2011) can be explained by aberrant morphogenesis of the node.
Interestingly, in the examples described above, the main causes of aberrant embryonic morphogenesis, even at the earliest stages, are thought to be defective establishment and/or maintenance of cell polarity.
This crossing scheme allows self progeny of the hermaphrodite to be identified by the absence of GFP LacI staining, ensuring that all examples of two GFP foci in the same nucleus resulted from defective SCC establishment in syIs44 heterozygotes rather than a recombination defect in syIs44 homozygotes.
It could therefore be that reduced sister centromere re-association observed in this experiment was due to defective cohesion establishment in S-phase rathan toan thethe requirement of Eco1 in mitosis.
Furthermore, we recently provided experimental evidence that Rage -/- mice are defective in the establishment and maintenance of dermal inflammation upon TPA stimulation accompanied by impaired tumor formation in a chemically induced skin tumor model [ 3].
This is defective corporate governance".
The functional genomics approach together with the establishment of defective biosynthesis steps in humans and generation of yeast and plant mutants in sterol biosynthesis enabled the elucidation of structural genes for the individual enzymes in sitosterol, ergosterol, and cholesterol formation.
We found no evidence of bias in grandparental origin suggesting that the imprinting defect occurred after erasure of the parental imprint and the defective imprinting resulted from disordered establishment or maintenance of the maternal allele imprint (which might be after fertilization).
One logical response to a defective Labour party is the establishment of a new party on the centre-left.
